Trailer
 | Toshiko Fujita as Rasetsu-jo (voice) |
 | Kunikazu Ishii as Osamu Tezuka (Child, voice) |
| Hiroshi Masuoka as Sa Gojo (voice) |
 | Toku Nishio as Cho Hakkai (voice) |
| Mari Shimizu as Mother (voice) |
| Kaneto Shiozawa as Sanzo (voice) |
 | Mayumi Tanaka as Son Goku (voice) |
 | Kousei Tomita as Higeoyaji (voice) |
 | Kiyoshi Kawakubo as Wan Laiming (voice) |
| Kyoji Kobayashi as Osamu Tezuka (Adult, voice) |
 | Takeshi Kusao as Osamu Tezuka (Teen, voice) |
 | Kenji Utsumi as Bull Demon King (voice) |
 | Mami Koyama as Lula / Kyoko Okamoto (voice) |
| Toshiko Fujita as Princess Iron Fan (voice) |
 | IchirÅ Nagai as Narrator (voice) |
| Hisashi Katsuta |
| Tetsuya Asado |
| Writing | |
| Rintaro | Screenplay |
Directing | |
| Rintaro | Director |
Visual Effects | |
| Osamu Tezuka | Character Designer |
Sound | |
| Yasunori Honda | Sound Director |
Writing | |
| Masami Hata | Screenplay |
Directing | |
| Masami Hata | Director |
Sound | |
| Katsuyoshi Kobayashi | Sound Director |
Camera | |
| Kinichi Ishikawa | Director of Photography |
Visual Effects | |
| Matsuyama Maya | Animation Director |
| Yoshiyuki Momose | Animation Director |
| Yoshiyuki Momose | Character Designer |
Art | |
| Katsuyoshi Kanemura | Art Direction |
Visual Effects | |
| Norihiro Matsubara | Character Designer |
Writing | |
| Kuniaki Yamashita | Screenplay |
Visual Effects | |
| Kanji Akahori | Animation Director |
Sound | |
| Haruhiko Maruyama | Music |
